Favorite kill, in a game

In recent years, it would have to be the room in Resident Evil 4 wherein you fight the two ogre-like creatures. There's a hatch in the middle of the floor, below which is a pool of lava. Lure the ogre over the hatch, ride a zipline to the other side of the room, throw a switch, and down he goes. What makes it memorable isn't the booby-trap kill, which has been done a thousand times before, but rather the way the creature thrashes around and throws drops of lava every which-way in its death throes. It takes a good 30 seconds or so to die, which really gives you the impression that their skin must be pretty damn thick. Any human would be dead instantaneously if dropped into LIQUID HOT MAG-MA.

Favourite kill of all time, hmmm...off-hand, I'd say one of the neatest was Reptile's "Invisible Slice" fatality. There's something really badass about seeing some poor bastard standing there, wobbling back and forth after having been shit-beaten by a ninja, and then hearing SHINNG! and the guy's torso flies off, lands 5 feet away, and a nice big ball of blood flies up and then splatters on the floor. Because of course blood always arranges itself into a perfectly spherical formation when shed by a ninja. Real ultimate power and all that noise.

So yeah, invisible slice FTW.

Jam it back in, in the dark.