I don't use the phrase and I'm religious. Why? I don't understand it.
Definitions from answers.com:
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Quote:
1. To make holy by religious rite; sanctify.
2. To make the sign of the cross over so as to sanctify.
3. To invoke divine favor upon.
4. To honor as holy; glorify: Bless the Lord.
5. To confer well-being or prosperity on.
6. To endow, as with talent.
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Out of these, only 5 seems to fit. So, I'd be saying, "God bestow well-being on you." Doesn't God have better things to do than fix everyone's sneezing problems? It'll go away on its own without Him...
Jam it back in, in the dark.