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That's exactly what I explained though. Assuming we were created by God, or a God in general, I would assume we started off with perfect DNA. Over time it's gotten less and less "perfect" so to speak via various transcription errors, which results in higher chances of birth defects from interbreeding. Way back at "the beginning," there wouldn't have been such a high chance from that.
EDIT^^^ Note that this is nothing more than an unfounded, untested theory. If the human race truly started out as 2 created human beings, this is how I would explain the problem of inbreeding.
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If it is true that we were perfect in the beginning and somehow became less perfect via transcription errors, the human race should have started degenerating a long time ago or become extinct. Becoming "not perfect" is not a good sign in the natural world. And if you say that transcription errors DO occur then you concede that genes CAN mutate. Either evolution has happened throughout the history of the earth (natural selection) or in your creationist theory evolution will happen because of these imperfections.
Just the example of the different skin colors cannot be explained without some sort of evolutionary process, or did Adam and Eve have multi colored babies as well?
This thing is sticky, and I don't like it. I don't appreciate it.