What are your essential programs?

Firefox - Abso-fucking-lutely the best browser ever to be used by FLEX. No way I'm ever going back to IE.
Winamp - Best music player I've run across. Ass-loads of skins, too.
VideoLAN Media Player - Plays nearly every movie file on God's green Earth.
BitLord - Best bittorrent client I've run across.
EditPlus 2 - Sophisticated text editor. Great for editing html and php.
JaSMiN 3D Color Changer 4 - Without it, I couldn't customize my desktop
DisplaySet - see above
Nero Burning ROM - For burning CDs.
Trillian Pro - Does what Miranda IM does.
RazorLAME - For mp3 encoding
LimeWire - For pulling files and music off Gnutella
eDonkey - One of my lesser favs.....too slow and bitchy.
Switch - Wonderful (and small) color picker.

Macromedia Studio MX - Mainly Dreamweaver MX for WYSIWYG web development and Freehand for vector art.
Adobe Creative Suite - It's bloated, but all of the programs in it (Photoshop, Illustrator, etc,) are the standard in graphic design.
Reactor Server - It's a Server In A Can™
SmartFTP - Preferred FTP client

Anti-Virus, firewall and scanning equipment:
Spybot S&D
Lavasoft AdAware SE
NOD32
ZoneAlarm Pro

Jam it back in, in the dark.